MAVENCLAD® IS THE ONLY ORAL IRT THAT SELECTIVELY REDUCES B AND T LYMPHOCYTES WITH MINIMAL IMPACT ON INNATE IMMUNE FUNCTION1,3,10-13,30,31
Proposed mechanism of action of MAVENCLAD®
Diagram is a hypothetical representation: illustrated elements do not represent actual quantities or proportions.
*The mechanism by which MAVENCLAD® exerts its therapeutic effects in MS is not fully elucidated, but its predominant effect on B and T lymphocytes is thought to interrupt the cascade of immune events central to MS1
**Median neutrophil and monocyte counts remain within normal range, however a decrease in neutrophil count was recorded as a common adverse drug reaction
†NK cells, neutrophils and platelets do not drop below the normal range1,9
IRT= Immune Reconstitution Therapy; MS=multiple sclerosis; NK=natural killer; Treg=regulatory T cell